Fluid Bed Equipment - Granulation & Pellet Coater- Combo Model

Application & Process

Prism Fluid Bed Equipments involves drying, cooling, agglomeration, granulation and coating of particulate materials. It is ideal for heat sensitive and non heat sensitive products in Pharmaceuticals, Biotech, Nutraceuticals, Cosmetic, Chemicals, Biochemical, Food, Dairy, Confectionery, Agrochemical, Herbals, Detergents and Pharma Institutes.

Depending on the application required Prism fluid bed Equipment can be configured into designs as follows :

1. The Fluid Bed Mixing and Drying Process: The Fluid Bed system has a bed of solid particles which are fluidized by passing a stream of air upward through a specially designed perforated sheet. The upward velocity of air is so maintained so as to slightly lift the solid particles and set them in motion. This motion can be utilized to bring about mixing as well as forward movement of the solids particles. The air is heated and the process hot air evaporates the fluid and dries the solids.
2. The Fluid Bed Processor with Top spraying system for Agglomeration and Granulation Process: The process is used in fluid beds to form granules form a fine powder. The fluidized powder is wetted with Binder solution by using top spraying system. The top spraying system provided with spraying nozzle and precise dosing peristaltic pump. The fluidized powder gets wetted and creates liquid bridges between particles and convert powder into granules. The continuous hot air ensure drying of granules and preventing of create lumps during process. Segregation of powder doesn’t take place as different powder is glued together on a micro scale. Since there is no impinging force in fluid bed equipments the granules are weak and having good solubility. Once the granules are made they are dried in the equipment using hot air. This technology used for formed granules for Tableting, capsule, dust free process, free flow properties, good dispensability and excellent solubility due to porous structure.
3. Fluid Bed Equipment with Wurster Coater Bottom Spray for Granules Coating or Pellet Coating:The Coater is capable of handling any of the following process.

• Aqueous or Solvent based solutions or suspensions
• Controlled release coatings
• Enteric Release coatings
• Fine particle coatings
• Active layering

This process is used to apply a coating to the granules or pellets. This technology known as wurster coater. In this process the spray is done inside a hollow cylinder (wurster) and from the bottom of this cylinder the pellets are allowed in small quantity to enter the hollow cylindrical tube (wurster). Then the particles are coming in contact with the coating solution from bottom spray guns in orderly manner then particles quickly moving upward the tubes to avoid agglomeration. Once they are outside the wurster compartment, they move downward outside the compartment where they gets dry process repeated until required coating layer achieved. Since the movement of the particle or pellets inside the wurster chamber totally controlled it ensures uniformity.

Salient Features

• Design is cGMP - Current Good Manufacturing Practices compliance.
• All contact parts AISI 316/316L & non contact parts AISI 304.
• Three piece construction & separate expansion chamber & retarding chamber cum filter bag housing
• Top Spraying system for Granulation and Wurster Coater- Bottom spraying system for Granules, Pellet & Tablet Coating.
• Granulation and Coating system with advance PLC controls system with HMI Touch screen.
• Spraying system with atomized spraying gun and high precise flow peristaltic pump.
• Dual Filter bag design to ensure continuous bottom spray during coating operation.
• Sampling pot on product container.
• Pneumatic Sealing of Filter Bag, Chambers and Product container by inflatable silicon gasket.
• Inlet Air Handling Unit with Air Filter (Pre, Fine & HEPA), Dehumidifier and Heat Exchanger.

Safety Features

• Product Bowl interlocking mechanism.
• Automatic Temperature & controls, Process cycle controls.
• Explosion flap at retarding chamber.
• Safe earthling system for static current.
• Air pressure switch installed to ensure pressure is in limit.
• Overload relay Protection and Emergency stop button.