Preparation Vessel & Liquid Syrup Manufacturing Plant

Application & Process

Prism has been designed & manufacturing preparation vessels and has consolidated a process knowledge concerning sterile injectable solution, dispersions, ophthalmic products, syrup and suppositories.

Preparation Vessels & Tank :

• Extremely hygienic processing.
• Least manual handling.
• Design compliance with cGMP
• Capacity up to 10,000 Liter.
• Product Contact AISI 316L
• Atmospheric, Vacuum or Pressure Operation.
• Jacket for heating & cooling.
• Vessel Inside Pressure (-1 /+2 Bar)
• Heating Jacket Pressure (-1 /+6 bar)
• Heating by steam or hot water circulation.
• Thermal Insulated.
• Mechanicals or Electro polishing of internal surface.
• Welded, flanged or hinged type cover
• Integrated Cleaning in Place-CIP.
• Sterilizing In Place-SIP as an Option.
• Portable execution on request.
• Validation protocols & Instrumentation celebration.

Variable Speed Agitation :

• Agitator can be top or bottom driven or magnetically driven.
• Propeller type, Anchor type provided with High speed disperser or rotor-stator homogenizer.
• Single or double mechanical seal.

Fully automatic Liquid Syrup Manufacturing Plant consisting of :

• Sugar Charging / Transfer System.
• Sugar Melting Vessel with mixing stirrer.
• Basket Filter & Transfer Pump.
• Syrup Manufacturing Vessel with stirrer.
• Inline Homogenizer.
• Zero Hold up Filter press.
• Storage Tank with stirrer.
• Interconnecting pipeline.
• Transfer Pumps.
• Integrated automatic control panel.
• Working Platform.

Salient Features

• Designed strictly compliance with the stipulation of cGMP.
• Product contact parts AISI 316 Quality and Non contact parts SS 304 Quality.
• Complete untouched operation for material transfer.
• Automated system for material transfer.
• Sugar Melting vessel with Anchor Stirrer and temperature controller.
• Syrup manufacturing vessel with Propeller Stirrer and temperature controller.
• Storage Vessel with Propeller Stirrer.
• Machine compact in designed with single base platform to enhance operating feasibility of plant.
• All vessels agitators having a Variable speed by VFD.
• Transfer Pump provided for material transfer from Sugar Melting Vessel to Syrup Manufacturing Vessel.
• Inline Homogenizer provided for material transfer from Syrup Manufacturing vessel to Storage vessel through Filter Press.
• Electric operating controls panel with push button and digital meter for control the process.

Safety Features

• Overload Relay and Emergency stop push button.
• Limit Switch for the Vessel lid close feedback.